Helix Immersion Programme Partners

Overview of the Project and Purpose

This role involves overseeing customer projects, managing existing accounts and internal developments within Allozymes, ensuring they are completed on time, within scope, and within budget.

Main Objectives and Responsibilities

• Work closely with the Chief Technical Officer to ensure successful delivery of project outputs to schedule and within budgets.
• Overseeing customer projects and internal developments within an organisation, from the start through to completion 
• Developing project scopes and objectives, involving all relevant stakeholders and ensuring technical feasibility
• Ensure resource availability and allocation for each project
• Formulate, organise and monitor inter-connected project
• Coordinate cross-project activities
• Develop detailed work breakdown structures and project plans to ensure delivery of agreed outcomes 
• Perform risk management to minimise project risks
• Create and maintain comprehensive project documentation
• Serve as the point of contact, to enhance collaboration between the business team and R&D team and ensuring timely execution of project
• Oversee project progress, addressing any issues with a focus on aligning Allozymes deliverables to the customers

Requirement of Qualifications, Skills and Experience

• Fresh PhD/Master’s in Science with commercial experience within the life science sector.
• Flexible approach to work assignments, ability to manage multiple and varied tasks and to prioritise the workload whilst maintaining attention to details
• Excellent interpersonal skills, verbal and written communication skills aligned with the ability to build and maintain strong relationships at sites and with service providers.
• >1 year working knowledge of program/project management preferred 
• Outstanding leadership and organisational skills

The biomechanical engineer will further the development of Castomize’s portfolio of medical device products from a biomechanics perspective. The current portfolio of products include orthopaedic casts and prosthetics.

This role is responsible for framing questions, conducting studies, analyzing data, interpreting results, communicating actionable insights, facilitating collaboration between internal product development teams and external problem owners, and prototyping ideas toward commercialisation. 

He/she will mainly be using 3D modelling design software and 3D printing techniques to conduct iterative prototyping and commercialization of products, along with other tasks related to product development and commercialization. 

Key Responsibilities 

• Use 3D modelling software to design Castomize’s products 
• Keep track of and report on product development progress 
• Use 3D printers, and oversee the 3D-printing process of prototypes to minimize errors 
• Provide inputs and suggestions to enhance the product development process 
• Work closely with the product development team to share knowledge and cross-develop 
• Liaise with external stakeholders regarding product development and production 
• In conducting studies, should have the ability to gather robust biomechanics data while gauging and incorporating subjective feedback, with the agility to adapt research methods 
• Data reduction, analysis, and interpretation 
• Clear, concise, actionable communication of research to designers and cross-functional audiences 
• Ability to zoom in and out - see the minute detail and big picture concurrently. 

Qualifications

• Master’s Degree or PhD in related fields 
• Proficiency in 3D modelling and design 
• 3-5 years research experience: musculoskeletal, soft tissue, prosthetic, exoskeleton biomechanics, and sports biomechanics 
• Experience with designing healthcare-related products is a plus 
• A passion for solving problems and providing value-added solutions with attention to detail 

About DotBio

DotBio is a highly innovative biopharmaceutical company with a mission to predict the most effective multi-functional antibody therapies cancer therapies and derisk the clinical development process. The company generates hundreds of multi-functional antibodies with good developability and screen them in parallel in high-throughput phenotypic assays (HTPAs) against diverse cancers. This combinatorial targeting approach allows to interrogate many immuno-oncology target combinations in parallel, generating a stack of data that can be analysed to identify the most potent and derisked antibodies to move into the clinic.

Project Description 

Are you a motivated professional in Pharmaceutical Science, Biochemistry, or a related field with a strong background in drug discovery? If so, we have an exciting opportunity for you!

DotBio is seeking an enthusiastic candidate to join our on-the-job training programme for Project Manager in IND-enabling studies. This programme is designed to provide hands-on experience and skill development, equipping participants with the knowledge and tools necessary to excel in managing IND-enabling studies including DMPK, toxicology, and manufacturing processes.

As a trainee in this programme, you will play a crucial role in supporting drug discovery and development by ensuring that the IND-enabling studies are conducted efficiently and effectively within the stipulated timeframes. You'll be immersed in real-world projects within the pharmaceutical and biotechnology sectors, gaining invaluable experience and insights.

Training Objective 

• Learn to identify, establish, negotiate, and maintain relationships with Contract Research Organisations (CROs) for both in vitro and in vivo investigations in IND-enabling studies
• Regularly review CRO performance to ensure timelines are met and data quality is maintained
• Review study-related documents (scope of work, protocols, amendments, and reports) for completeness, accuracy, and consistency with regulatory guidance
• Ensure all IND-enabling activities comply with relevant regulatory requirements and industry standards
• Oversee the execution of IND-enabling studies, ensuring adherence to project plans and timelines
• Monitor project progress and performance, addressing any issues or deviations
• Get acquainted with project management tools and software
• Provide regular project updates, highlighting progress, challenges, and necessary adjustments

Requirements

• PhD or MSc in a relevant field
• Solid understanding of IND-enabling studies’ principles and drug discovery
• Broad experience in biologics drug development and pharmacology
• Ability to interpret complex scientific data and make informed project decisions
• Strong organisational and time management skills
• Excellent interpersonal and communication skills along with a collaborative mindset
• Experience with regulatory submissions for biologics and/or small molecules would be an advantage
• Commitment to maintaining quality standards and regulatory compliance

Skills to be learnt

• Project Management
• Product Development
• Chemistry and Manufacturing Controls / Process Engineering
• Communication Skills
• Stakeholder Management
• Leadership

About Hilleman Laboratories

Hilleman Laboratories was established in 2009 as an equal joint venture between Merck Sharp & Dohme Corp. (MSD), a global research-driven pharmaceutical company and Wellcome Trust, a global charitable foundation dedicated to health. Hilleman Laboratories’ mission is to develop affordable vaccines and biologics against infectious diseases that affect low- and middle-income countries.

Hilleman Laboratories is establishing a first-of-its-kind vaccine and biologics development and manufacturing hub in Singapore comprising a 30,000 square foot current Good Manufacturing Practices (cGMP) facility and a state-of-the-art research and development facility.

Objectives

• Act as user representative/area owner in terms of technical transfer of process and product from R&D and CMC to GMP clinical manufacturing of different modalities and platforms to meet tech transfer objectives and timeline.
• Perform manufacturing and maintenance activities to ensure that critical manufacturing operations are on track and within budget.

Responsibilities

• Execute manufacturing activities in a safe and compliant manner.

• Ensure data is recorded in an ALCOA manner in the Manufacturing Batch Records (MBRs) and forms.

• Provide input to operation and equipment in the tech transfer activities of new product/process.

• Draft, author and/or provide inputs in documents consisting of but not limited to, facility fit assessment, user requirements, raw material identification, batch records, SOPs and process recipes.

• Perform front line troubleshooting of Fill finish equipment.

• Be part of the Total Productive Maintenance for Fill finish equipment.  

• Coordinate with relevant departments and stakeholders and track progress of operation to ensure project milestones are met.

• Perform and lead root cause analysis for operational related deviations and investigations using established problem-solving tools.

• Complete required training on time to ensure operations are conducted in a safe manner.

• Support process/equipment qualification/validation activities and studies.

• Front auditors during regulatory audits as the SMEs of the department.

• Perform cleaning of equipment and cleanrooms as and when necessary.

• Perform basic 5S housekeeping.

• Any other duties as assigned by supervisor.

Education, behavioural competencies and skills:

• Master's degree in an engineering/scientific discipline (Bio/chemical engineering/life science/biology/chemistry) with 2-6 years relevant industry experience.
• Plant start-up or commissioning and/or operational experience in biologics and/or vaccines.
• Experience/knowledge of cGMP practices as applicable to fill finish processes is required.
• A thorough knowledge of Good Documentation Practices (GDP) and Current Good Manufacturing Practices (cGMP).
• Well-organised and detail-oriented, with ability to effectively prioritise tasks with agility, eager to learn, interact and collaborate effectively with various stakeholders in a team environment and consistently demonstrate reliability and responsibility.
• Must be a team player with good working ethics, initiative, diplomacy, positive influencing abilities and drive.
• Good oral communication and demonstrable, exemplary writing skills.
• Experience with problem solving and statistical tools will be an advantage.

Skills to be learnt

• Chemistry and Manufacturing Controls / Process Engineering
• Chemical Engineering
• Fill Finish
• cGMP
• vaccine
• Biology

About ImmunoQs

ImmunoQs is a spin-off company from the Agency for Science, Technology and Research (A*STAR), Singapore. We help clinicians and drug developers to generate and analyse multiplex immunofluorescence images and spatial omics datasets, so that more effective drugs and more precise diagnostic assays can be developed. Our unique digital analytics platform allows researchers and clinicians to organise, visualise, and analyse large spatial omics data collected from pre-clinical to clinical studies. Our customers include leading medical centers, research institutes, and pharmaceutical companies in Singapore and other countries.

Overview

The candidate will work closely with the Digital Analytics Lab Director to help ImmunoQs’ clients or collaborators to analyse multiplex tissue images and spatial transcriptomics data. The candidate will also help to develop new data analytics workflow or products to make new spatial omics technologies more accessible to clinicians and researchers.

The candidate will have the opportunity to learn bioinformatics and data analysis software development process, and prepare for a possible career in this exciting field. He/she will have the opportunity to work in an interdisciplinary and start-up environment and learn how computational biology can help clinicians to fight cancers.

Responsibilities

• Perform image processing and quantify cellular phenotypes using ImmunoQs’ data analytics platform.

• Develop and implement data analysis workflow for new spatial omics technologies.

• Perform image quality control and annotate regions of interest from tissue images.

• Generate heatmaps, bar charts, or other graphs to represent the results.

• Document analysis methodologies, results, and records.

• Prepare reports and presentations to our clients or collaborators.

• Provide technical support and assistance to clients or collaborators.

• Support business development strategies and marketing efforts.

• Learn the latest spatial omics instruments, techniques, and data processing and analysis methodologies by reading papers and attending/participating in appropriate workshops, seminars, and courses.

Requirements

• Master or Ph.D. in computational biology, bioinformatics, bioengineering, biomedical science, biological science, life sciences, computer science, or other relevant fields.

• Proficiency in programming languages and software tools commonly used in bioinformatics and tissue image analysis, including R and Python, is required. Previous experience in using ImageJ/Fiji or QuPath is highly desirable.

• Good knowledge in data normalisation, RNA expression analysis, biological pathway enrichment analysis, clustering analysis, and basic machine learning algorithms are required. Previous experience in analysing spatial transcriptomics data (such as Visium, CosMx, GeoMx, or Stereo-seq) is highly desirable.

• Good knowledge in molecular biology, transcriptomics, cancer, and immunology. Previous experience in microscopy, imaging, or tissue staining is highly desirable.

• Preferably with 1 or 2 years of experience working in a research laboratory.

• Excellent analytical and problem-solving skills, with the ability to analyse complex data and draw meaningful conclusions.

• Strong attention to detail and ability to implement quality controls for reliable and accurate data analysis.

• Excellent verbal and written communication with good documentation skills.

• Ability to work collaboratively in a fast-paced and dynamic startup environment.

Skills to be learnt

• Product Development

• Machine Learning

• Product Management

• Data Analytics

• Marketing

• Data Visualisation

About Mirxes

An RNA technology company that develops and commercialises accurate, non-invasive, and affordable blood-based miRNA test kit products for the early detection of cancer and other diseases.

Job Description

This role will help to maintain, optimise, build and run bioinformatic pipelines, including those from whole genome sequencing and or whole genome methylation sequencing.

The candidate will work closely with other research scientists and will be responsible for running various data analysis pipelines to process genomic data generated from Next-Generation Sequencing (NGS) and/or other sequencing platforms.

Roles and Responsibilities:

• Manage large data sets generated from sequencing operation and monitor the data quality
• Maintain and update scripts and or computing systems for various bioinformatics pipelines (e.g. WGS, WGMS, RNA etc)
• Be competent in validating, optimising, and customising existing workflows or building new workflows to meet project requirements

Minimum Requirements

• PhD in related Science background
• MSc in related Science background with >2 years experience
• Experience working with new generation sequencing data (NGS) (e.g. WGS, WGMS) including annotation, QTL analysis etc.
• Good working knowledge in:
  1. Linux environment
  2. Languages: Shell scripting, R and/or python
  3. Working with workflow management system
• Good understanding and proficiency in handling and processing sequencing data using bioinformatics tools and databases
• AWS knowledge is desirable but not essential
• Good verbal communication, interpersonal skills and ability to work in a team

About Mirxes

An RNA technology company that develops and commercialises accurate, non-invasive, and affordable blood-based miRNA test kit products for the early detection of cancer and other diseases.

Project Description

The Genomics clinical lab is seeking a Product Developer to support NGS assay development. The ideal candidate would be well-rounded in molecular biology techniques and have a passion for implementing NGS workflow in a commercial service lab environment. Candidates with NGS, clinical experience or exposure will be preferred.

Roles and Responsibilities

• Plan assay development work, such as design and run new assays for sample preparation, libraries preparation and sequencing.
• Execute manual and automated experiments in assay development work.
• Write manual and automation versions of tested SOP and write validation reports.
• Perform sample QC, prepare sequencing libraries, and perform ultra-high throughput sequencing to support service operation.
• Receive trainings on genomics sample preparation, library preparation, and high and ultra-high throughput NGS sequencing workflows.
• Work with Research Scientist on assay development in areas such as metagenomics sequencing, single cell technologies etc.
• Analyse sequencing data and report results in a timely manner.
• Assist in troubleshooting and ensuring proper documentation of all processes.
• Interact with bioinformaticians and evaluate bioinformatics output.
• Maintain lab equipment, inventory & documentation by quality requirements.
• Supervise and train junior staff.
• Other ad-hoc projects as required.

Minimum Qualifications

• Master’s in molecular biology or related field.
• Meticulous and attentive to details
• Good communication and interpersonal skills
• Have a positive, proactive, can-do attitude.
• Keen to learn and good team player.

About

Founded in 2020, N&E Innovations is a Singapore-based medtech company that has innovatively engineered ViKANG99, a natural antimicrobial agent, which is non-toxic and certified to eliminate virulent particles including Coronaviruses with long-term effect. Derived from recycling edible fruit residue, ViKANG99 enables the creation of a circular economy and reduction of carbon footprint. We seek to both protect users and to ensure sustainability of our environment and ecosystem via such upcycling of wastes. 

Project Description

We seek an unendingly curious research scientist to champion cutting-edge investigative endeavours.  

You will  

• Detect consequential knowledge gaps, formulate comprehensive research strategies, and execute rigorous methodological and analytical steps. 

• Pitch your projects for publication, both regionally and internationally.  

• Assist in developing products by identifying potential products, conducting market research, generating product requirements, determining specifications, production timetables, pricing, and time-integrated plans for product introduction, and developing marketing strategies. 

Roles & Responsibilities

Drive business growth 

• Responsible for managing new product launches, product improvements, line extensions, or limited time offers from concept to successful launch within agreed time frames. Development includes attention to aspects such as Technical & Financial feasibility, formulation accuracy, execution of Pilot Plant and plant trials and confirming commercial stability. 

• Development covers aspects such as Technical & Financial feasibility, commercial plans support, and operational stability. 

• Understands state of the business and leverages knowledge to drive down project time/costs. Anticipates obstacles affecting other business functions. 

• Remains well informed of the state of the business and leverages knowledge to drive down project time/costs. Anticipates obstacles affecting other business functions. 

• Assesses market competition by comparing the company's product to competitors' products. 

• Recommends the nature and scope of present and future product lines by reviewing product specifications and requirements; appraising new product ideas and/or product or packaging changes. 

Innovation/Creativity 

• Possesses curious and open mindset with thirst for learning and new knowledge, provide innovative, timely, and cost-effective improvements, concepts, developments, or scientific insight and understanding with respect to new or existing products or processes. 

Technical Expertise 

• Provides technical direction and leadership within the department as an expert in a specific discipline who keeps current with the latest development trends and technology through investigation, training, and communications. 

• Upholds quality image standards. Appropriately addresses both project and non-project related quality or safety issues when encountered. 

• Organizes & executes all aspects of lab to bulk testing. Assists Food Technologist in making preparation for plant testing. 

• Maintains professional and technical knowledge by attending educational workshops; reviewing professional publications; establishing personal networks; participating in professional societies. 

• Conduct experiments in labs to analyse substances, develop new products or improve existing ones. 

• Customize formulas and use different reagents for testing and application. 

People Management 

• Sets workload and performance expectations, provides evaluations, identifies, and bridges developmental needs for direct report(s) which may consist of lab assistants and/or interns. 

Stakeholder Management 

• Follow up with vendor for scale up manufacturing of disinfectant and other products developed. 

Minimum Requirements

• PhD in Organic chemistry, Biochemistry, Biotechnology, Microbiology, or relevant discipline from a reputable institution. 

• Experience as Scientist/Chemist/Product Developer and has prior experience commercializing 1-2 products related to food waste valorisation/anti-viral, anti-microbial or anti-bacterial. 

• Minimum 1-3 years of R&D experience in a scientific laboratory role, ideally within a biological/pharmaceutical laboratory environment. 

• Hands-on experience in cell culture and in small molecule/biomolecule/biopolymer design, synthesis, modification, and characterization 

• Solid knowledge on chemical reactivity and material structure-property relationship. 

• Proficient in kilogram-scale production of liquid formulations and powder-based products. 

• Skilled in drafting patent disclosures, performing prior art searches and competitor analysis. 

• Demonstrated experience of ethical leadership, with steadfast resolve and personal integrity. 

• Meticulous attention to detail and accuracy. 

• Patience and determination. 

• Outstanding verbal and written skills. 

Skills to be learnt 

• Formulation 

About

NousQ is a new medtech startup company that develops a surgical medical device in the Ear, Nose and Throat (ENT) field to address a key unmet healthcare need in glue ear treatment. It offers a novel solution by providing the world's first automated device that could revolutionise the current way of treating the condition. 

NousQ is proud to be the Top 5 winners of the Medtronic APAC Innovation Challenge 2022, and is honoured to be the winner of other innovation challenge such as MedTech Innovator Challenge APAC 2022 Accelerator Cohort, Victoria Health Week MedTech Festival as well as the recent China TusStar APAC Challenge. 

https://www.nousq.com/ 

Project Description

NousQ is a Singapore-based company focusing on research, design, develop, manufacture and commercialize medical technology and solutions that optimize healthcare delivery and serve large unmet needs for patients. The focus is on patient-centric solutions that patients really want and need.  Currently, NousQ is looking for a passionate firmware engineer to join our growing team.   

We want to introduce the world to CLiKX, a revolutionary and cutting-edge robotic medical device. CLiKX will transform glue ear surgeries by moving the procedure from the operating room to an outpatient setting. As a result, the time, money, and resources needed for such a procedure are significantly reduced.  

You will join our team of pioneer innovators in bringing CLiKX to the millions of untreated children who suffer from glue ears. 

Roles & Responsibilities

• Participate in ideation, conceptualization, design and iteration, verification and validation, manufacturing support for new product pipeline involving embedded system. 

• Be involved in design reviews to identify issues and derive robust solutions that meet the intended use, safety and effectiveness, as well as quality of the product. 

• Collaborate with manufacturing partners to communicate design concepts, technical and/or business trade-offs, and engineering solutions. 

• Perform firmware engineering tasks including:
  (1) Translate/refine high-level requirements into the architecture and engineering specifications of the firmware system;
  (2) Design, develop, integrate and debug/troubleshoot the embedded system/MCU-related hardware to meet the defined objectives, targeted cost and schedule;
  (3) Support the development and execution of relevant test plans, including unit test, integration test and system test to verify and validate that the product can meet all requirements;
  (4) Support functional and reliability tests to ensure safety and performance of the overall product systems. 

• Generate and maintain the necessary documentation for the firmware systems, including design documents, firmware architecture, schematics, SOP/work instructions, Device Master Record (DMR) and other documentations needed to meet the regulatory requirements such as Design History File (DHF), IEC62304, ISO13485 & FDA 21 CFR Part 820. 

• Oversee firmware design change orders and support any relevant verification and validation activities. 

• Support ad-hoc administrative duties as and when required to ensure smooth operation of the company’s activities. 

Minimum Requirements

• Master’s/PhD degree in Biomedical/Electronics/Computer Engineering with experience in embedded system development. The engineer will be a part of the startup team focusing on product realisation process. 

• Good understanding of product realisation process and preferably with prior experience or interest in embedded system design and development processes. 

• Relevant experiences include coding with programming language such as C/C++ and/or competent in applying other similar IDEs/toolchains for firmware development. 

• Knowledgeable in quality concepts including verification and validation, and reliability testing. 

• Good understanding of medical device software regulatory requirements, such as IEC62304 and/or FDA Software in Medical Device requirements. 

• Excellent communication skills in spoken and written English and good inter-personal skills to engage and interact with team members, vendors, consultant and any potential third party. 

• Possess a high level of integrity, independent, self-motivated and enjoy working in a fast-paced startup environment. 

• Experience in electronic circuit design and/or AI/ML-related development is a plus. 

Skills to be learnt

• Electronics 

• Printed Circuit Board (PCB) Design 

• Product Development 

• Product Management 

• Usability Design 

• Hardware Design 

​​​​​​​About PairX Bio

PairX Bio is a precision oncology company developing next generation therapeutics targeting cancer-associated antigens derived from alternatively spliced proteins. The PairX Bio discovery platform is built upon a deep understanding of mRNA splicing biology and robust validation of identified targets. The technology was developed and spun out from Professor David Epstein’s lab at Duke-NUS Medical School.

Job Description

Join our innovative and exciting oncology startup as a Bioinformatician, where you'll gain exposure to the early-stage biotech environment, develop your critical thinking, and participate in making informed decisions about target selection. Leveraging your expertise in bioinformatics and computational biology you will collaborate closely with our team of scientists and play a pivotal role in analysing and interpreting complex transcriptomic and molecular data to contribute to the identification of novel therapeutic targets and the development of cutting-edge treatments.

Responsibilities

1. Develop statistical and machine learning methods to identify therapeutic targets.
2. Contribute to development of data analysis workflows for NGS data, ensuring reproducibility and scalability of analyses.
3. Communicate and work with the discovery team to design experiments and validate findings.
4. Document analysis workflows and their associated data flow into SOPs, work instructions, protocols, and other technical documentation.
5. Manage and organise multiple target programs concurrently.
6. Present findings and insights to both technical and non-technical audiences, including team members, management, and potential collaborators.

Job Requirements

1. Ph.D. in Computational Biology, Bioinformatics, Biostatistics, or a related field, with experience in analysis of large-scale omics data sets (NGS data).
2. Strong programming skills in R, Python, and/or other languages commonly used in bioinformatics and data sciences.
3. Proficiency with Unix-based systems and running or scripting applications from the command line.
4. Familiarity with public genomics databases/resources and data processing
5. Knowledge of statistical analysis, machine learning, and data visualisation techniques applied to biological data.
6. Knowledge of cloud computing environments (especially AWS), server maintenance and upkeep.
7. Previous experience in the oncology space and downstream molecular biology analysis is a plus.
8. Experience in RNA splicing analysis is highly desirable.
9. Strong communication skills and ability to collaborate effectively in a multidisciplinary team environment.

This project is in partnership with Trinity Innovation Bioventure Singapore (TIBS) and National Health Innovation Centre Singapore (NHIC). 

About Trinity Innovation Bioventure Singapore

Trinity Innovation Bioventure Singapore (TIBS) is a licensed biomed venture capital fund focusing on innovation and value investment with deep insight and experience on Asia markets. The team is led by industrial veterans who have managed multiple VC funds and invested in over dozens of biotech companies. 

Job Description 

TIBS is seeking an entrepreneurial Venture Building Lead to support the incubation and growth of early-stage biotech companies in Singapore. The Venture Building Lead will work closely with scientific researchers, entrepreneurs, investors, and other stakeholders to transform scientific breakthroughs into globally competitive biotech companies. This role requires a combination of drug discovery knowledge and business skills to support early-stage companies in building a strong foundation for growth. 

Roles and Responsibilities: 

• Lead the venture building projects and support the collaborations with research institutes in Singapore.

• Source investment opportunities to translate scientific breakthroughs into a corporate venture. 

• Lead or support new venture building including research plan, budget forecast, market landscape analysis, team recruiting and risk control plan. 

• Conduct market research to understand the demand, competition, and feasibility of new ventures. 

• Perform research in the scientific field and gather intelligence by establishing the key business drivers, determining the barriers to entry and identifying the key competitors. 

• Support fundraising activities for the incubation projects. 

• Build partnerships with key players in the biotech ecosystem, including research centres, corporate partners, and government agencies. 

• Offer hands-on support to startups in areas like project management, strategic planning, and problem-solving. 

Requirements 

• Education: Advanced degree in biomedical field (e.g., Biology, Medicine, MD). 

• Experienced with biotech startups, research institutes, or a similar field. 

• Industry Knowledge: Good understanding of drug discovery protocol, and the biotech startup landscape. 

• Financial Skills: Experience with financial modelling and venture financing is a plus. 

• Analytical Skills: Ability to collect, organize, analyze, and disseminate significant amounts of information with attention to detail and accuracy. 

• Others: Good interpersonal skills, and ability to persuade, negotiate and influence 

About Xenolis

Xenolis Pte Ltd is a platform-based life sciences company focusing on the development of synthetic aptamers. Leveraging on our unique technologies, we are developing DNA and RNA-based solutions in their field of use. We are currently seeking motivated Research Scientists to join our R&D team in Singapore.

Responsibilities

• Generate and characterise nucleic acid aptamers
• Develop a new biotechnology based on genetic alphabet expansion
• Perform a variety of assays (e.g. cell signalling bioassay, internalisation/trafficking assay, protein-based and cell-based binding assays) and immunological-related assays (e.g. ELISA, flow cytometry)
• Perform mammalian cell culture experiments and maintenance
• Maintain detailed documentation of research, protocols, SOPs, inventories, maintenance logs, etc
• Take on laboratory management duties including but not limited to procurement, inventory management, laboratory equipment maintenance
• Ensure compliance with standard operation procedures, in-house safety measures and other industry practices

Job Requirements

• Knowledge of basic chemistry/biology and molecular biology, including nucleic acid research
• PhD, a Master degree, or a Bachelor degree in a Life Science, Biological Science, Biochemistry or related disciplines
• Wet lab experience with chemistry and biology for nucleic acids and proteins
• Proficient with high-dimensional data analysis, and familiar with the use of genomic analysis, computational biology, statistical and visualisation tools
• Experienced in cell culture and molecular lab techniques
• Excellent organisational skills
• Excellent interpersonal and verbal/written communication skills
• Self-motivated with a proactive attitude
• Strong troubleshooting and problem-solving skills
• Ability to work independently and collaboratively with team members in a fast-paced biotech startup